|
What is Systems Biology?
Technological breakthroughs, including those enabled by the Human Genome Project, are providing new opportunity to understand the complex systems and networks responsible for most important biological functions. Systems biology is a powerful approach to studying genes and proteins made possible through these technological advances. Unlike traditional biology that has examined single genes or proteins in isolation, systems biology simultaneously studies the complex interaction of many levels of biological information - genomic DNA, mRNA, proteins, functional proteins, informational pathways and informational networks -to understand how they work together.
Systems biology will help unravel the mysteries of human immunity and identify strategies for preventing diseases such as cancer, arthritis, and AIDS. While the challenges are breathtaking - the human brain, for example, has ~1012 nerve cells with ~1015 connections - so are the opportunities to develop revolutionary medical applications that benefit humankind.
什么是系统生物学?
技术上的突破,包括人类基因组工程(HGP)推动的,为理解与最重要的生物学功能相关的复杂系统和网络提供了新的机会。系统生物学是一种强大的研究基因和蛋白质的策略,这因为技术上的进步而成为可能。传统的生物学独立的检测单个基因或者蛋白质,与之不同的是,系统生物学同时研究许多水平上生物信息——基因组、DNA、mRNA、蛋白质、功能蛋白质、信息通路以及信息网络——的复杂的相互作用,从而理解他们如何共同发挥作用。
系统生物学可以帮助解开人类免疫之谜,提供防治象癌症、关节炎以及爱滋等疾病的方法。挑战是惊人的——例如人类大脑具有大约10 12个神经细胞,大约10 15个联系——发展造福人类的革命性的医疗手段的机遇也是惊人的。 |
|