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美国国立卫生院NIH

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发表于 2006-3-11 20:10:04 | 显示全部楼层 |阅读模式
<p><strong><font size="3">NIH组织结构和运作方式</font></strong></p><p><table cellspacing="0" cellpadding="0" width="80%" bgcolor="#ffffff" border="0"><tr><td align="center" bgcolor="#ffffff" height="5">鲁白 </td></tr><tr><td align="center" bgcolor="#ffffff" height="62"><table cellspacing="0" cellpadding="0" width="526" border="0"><tr><td width="524" colspan="2"><font size="2">    NIH的历史可追溯到1887年在纽约的StatenIsland建立的卫生学实验室。该实验室主要从事传染病,流行病,细菌学等方面的研究,并生产疫苗和其他生物制剂。1891年实验室迁移到华盛顿。1930年卫生学实验室更名为国立卫生研究院。1938年,NIH搬至华盛顿北郊、马里兰州的贝塞斯达(Bethesda)。 <p>  NIH的初期只有院内研究。对院外研究项目发放资助基金是在二战时才开始的。上世纪50年代至60年代的征兵制法案对极大地影响了NIH乃至美国生物医学史。为了逃避去越南战场服役,很多非常优秀的青年医师纷纷选择来NIH做研究,以在国家机构服务来完成征兵制法案规定的义务。他们当中的许多佼佼者被生物医学研究所吸引,最终选择了弃医而从事科研。这些人后来或者去各医学院校任教授,或者留在NIH从事院内研究。美国今天之所以能有如此兴旺的生物医学事业,这批科技精英功不可没。 </p><p>  NIH的院长由美国总统提名,国会听证批准。其经费由国会直接拨款。虽然NIH在名义上附属于美国卫生部,但是实际上它是一个独立的科研机构。NIH各研究所往往以人的器官或疾病来命名。每个研究所有一位所长,主管全国范围内与该所有关的科技政策、科研方向及院外研究的资助。而院内研究则由其领导下的一位科研所长负责,主管所内几十个基础和临床系科。每个系科又有3至8个独立的实验室,由一位经过筛选的科学家担任主任。 </p><p>  常务副院长负责整个NIH院内研究事务。在常务副院长的主持下,科研所长联席会议一月举行两次,讨论政策制定和公众关心的事务。许多关于内部项目的重要建议和决定都是在该会上制定。科研所长负责该研究所内独立科学家(即实验室主任)的招聘、评估、晋升、解聘,以及所内经费、实验室面积和其他资源的分配等,是所内事务重要的决策者。 </p><p>  所内独立科学家分为两个级别:终身科学家(tenuredinvesti鄄gators),相当于大学的终身教授;终身途科学家(tenur-trackinves鄄tigators),相当于大学未获终身教职的助理教授和副教授。 </p><p>  NIH对终身科学家的定义是:“终身职称是对独立高级研究员作出的长期稳定的承诺,包括薪水、独立的资源(人员,预算和实验室面积),但他们同时也要受到的定期专家评审。研究所根据终身研究员的工作数量和质量来分配资源。授予终身职称乃是对高级研究员成就和今后潜力的认同,长时期的高质高产是惟一的标准。”NIH现有终身科学家2000多名,他们是NIH的核心和灵魂。他们要灵活地抓住新机会,将新思想付诸实践,长期进行重要的和高度创新的科学研究。NIH非常珍视这批高级人才,除了保护其学术研究自由外,还赋予终身科学家长期稳定的经费和资源,让他们免于费时且不确定的基金申请。这是NIH能够招募到并留住世界上优秀科学家的一个法宝。终身职称只在犯了不法行为才终止,但这很少发生。 </p><p>  NIH科研的另一主要力量是终身途科学家。他们是来自世界各地优秀学府并经过严格博士和博士后训练的年轻科学家。NIH在延揽招聘终身途科学家方面有一套严格完整的程序,招聘工作由一个专门的招聘委员会负责。招聘委员会的主席必须是非本系科的科学家,成员必须有非本研究所的科学家、妇女代表、少数民族代表,并由NIH常务院长批准。招聘时,首先是在《科学》和《自然》等全球发行的科学杂志上登广告,对空缺职位作描述。应聘人除了履历、代表论文外,还要交一份今后研究工作的详细计划。每个申请人都要有3位著名科学家的推荐。然后通过招聘委员会的反复挑选,选出3至5位来NIH进行1至2天的面试,竞争一个工作岗位。候选人要作一小时的报告,介绍自己过去的工作和未来的计划,还要与十几个科学家进行面谈。最后,招聘委员会进行讨论并投票,选出第一候选人。该候选人如接受NIH的位子,将获得一份终身途科学家协议,它清楚地规定了该候选人将得到的独立资源:实验室面积、人员数和预算。终身途科学家任期6年(临床科学家是8年)。在此期限内,他们必须接受2次由外部科学家组成的科学顾问委员会的评审。如果工作出色,经过全院终身职位委员会的审批,可以晋升为终身科学家。 </p><p>  (文章作者系美国NIH儿童发育研究所神经发育和可塑性研究室主任) </p></font></td></tr></table></td></tr></table></p>
 楼主| 发表于 2006-3-11 20:21:13 | 显示全部楼层

美国国立卫生院NIH

<p>与信息有关的研究所和中心有:</p><p> National Institute of Biomedical Imaging and Bioengineering (NIBIB) - Est. 2000<br />NIBIB improves health by promoting fundamental discoveries, design and development, and translation and assessment of technological capabilities in biomedical imaging and bioengineering, enabled by relevant areas of information science, physics, chemistry, mathematics, materials science, and computer sciences. <br /> Center for Information Technology (CIT formerly DCRT, OIRM, TCB) - Established in 1964<br />CIT incorporates the power of modern computers into the biomedical programs and administrative procedures of the NIH by focusing on three primary activities: conducting-computational biosciences research, developing computer systems, and providing computer facilities. </p><p>其它研究所和中心是:</p><p> National Cancer Institute (NCI) - Established in 1937<br />NCI leads a national effort to eliminate the suffering and death due to cancer. Through basic and clinical biomedical research and training, NCI conducts and supports research that will lead to a future in which we can prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases. <br /> National Eye Institute (NEI) - Est. 1968<br />NEI conducts and supports research that helps prevent and treat eye diseases and other disorders of vision. This research leads to sight-saving treatments, reduces visual impairment and blindness, and improves the quality of life for people of all ages. NEI-supported research has advanced our knowledge of how the eye functions in health and disease.<br /> National Heart, Lung, and Blood Institute (NHLBI) - Est. 1948<br />NHLBI provides leadership for a national program in diseases of the heart, blood vessels, lung, and blood; blood resources; and sleep disorders. Since October 1997, the NHLBI has also had administrative responsibility for the NIH Woman's Health Initiative. The Institute plans, conducts, fosters, and supports an integrated and coordinated program of basic research, clinical investigations and trials, observational studies, and demonstration and education projects. <br /> National Human Genome Research Institute (NHGRI) - Est. 1989<br />NHGRI supports the NIH component of the Human Genome Project, a worldwide research effort designed to analyze the structure of human DNA and determine the location of the estimated 30,000 to 40,000 human genes. The NHGRI Intramural Research Program develops and implements technology for understanding, diagnosing, and treating genetic diseases. <br /> National Institute on Aging (NIA) - Est. 1974<br />NIA leads a national program of research on the biomedical, social, and behavioral aspects of the aging process; the prevention of age-related diseases and disabilities; and the promotion of a better quality of life for all older Americans. <br /> National Institute on Alcohol Abuse and Alcoholism (NIAAA) - Est. 1970<br />NIAAA conducts research focused on improving the treatment and prevention of alcoholism and alcohol-related problems to reduce the enormous health, social, and economic consequences of this disease. <br /> National Institute of Allergy and Infectious Diseases (NIAID) - Est. 1948<br />NIAID research strives to understand, treat, and ultimately prevent the myriad infectious, immunologic, and allergic diseases that threaten millions of human lives. <br /> National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - Est. 1986 <br />NIAMS supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases, the training of basic and clinical scientists to carry out this research, and the dissemination of information on research progress in these diseases. <br /> National Institute of Child Health and Human Development (NICHD) - Est. 1962<br />NICHD research on fertility, pregnancy, growth, development, and medical rehabilitation strives to ensure that every child is born healthy and wanted and grows up free from disease and disability. <br /> National Institute on Deafness and Other Communication Disorders (NIDCD) - Est. 1988<br />NIDCD conducts and supports biomedical research and research training on normal mechanisms as well as diseases and disorders of hearing, balance, smell, taste, voice, speech, and language that affect 46 million Americans. <br /> National Institute of Dental and Craniofacial Research (NIDCR) - Est. 1948<br />NIDCR provides leadership for a national research program designed to understand, treat, and ultimately prevent the infectious and inherited craniofacial-oral-dental diseases and disorders that compromise millions of human lives. <br /> National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) - Est. 1948<br />NIDDK conducts and supports basic and applied research and provides leadership for a national program in diabetes, endocrinology, and metabolic diseases; digestive diseases and nutrition; and kidney, urologic, and hematologic diseases. Several of these diseases are among the leading causes of disability and death; all seriously affect the quality of life of those who have them. <br /> National Institute on Drug Abuse (NIDA) - Est. 1973<br />NIDA leads the nation in bringing the power of science to bear on drug abuse and addiction through support and conduct of research across a broad range of disciplines and rapid and effective dissemination of results of that research to improve drug abuse and addiction prevention, treatment, and policy. <br /> National Institute of Environmental Health Sciences (NIEHS) - Est. 1969<br />NIEHS reduces the burden of human illness and dysfunction from environmental causes by, defining how environmental exposures, genetic susceptibility, and age interact to affect an individual's health. <br /> National Institute of General Medical Sciences (NIGMS) - Est. 1962<br />NIGMS supports basic biomedical research that is not targeted to specific diseases. NIGMS funds studies on genes, proteins, and cells, as well as on fundamental processes like communication within and between cells, how our bodies use energy, and how we respond to medicines. The results of this research increase our understanding of life and lay the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS also supports research training programs that produce the next generation of biomedical scientists, and it has special programs to encourage underrepresented minorities to pursue biomedical research careers. <br /> National Institute of Mental Health (NIMH) - Est. 1949<br />NIMH provides national leadership dedicated to understanding, treating, and preventing mental illnesses through basic research on the brain and behavior, and through clinical, epidemiological, and services research. <br /> National Institute of Neurological Disorders and Stroke (NINDS) - Est. 1950<br />The mission of the NINDS is to reduce the burden of neurological diseases -- a burden borne by every age group, every segment of society, and people all over the world. To accomplish this goal the NINDS supports and conducts research, both basic and clinical, on the normal and diseased nervous system, fosters the training of investigators in the basic and clinical neurosciences, and seeks better understanding, diagnosis, treatment, and prevention of neurological disorders. <br /> National Institute of Nursing Research (NINR) - Est. 1986<br />NINR supports clinical and basic research to establish a scientific basis for the care of individuals across the life span--from the management of patients during illness and recovery to the reduction of risks for disease and disability; the promotion of healthy lifestyles; the promotion of quality of life in those with chronic illness; and the care for individuals at the end of life. This research may also include families within a community context, and it also focuses on the special needs of at-risk and under-served populations, with an emphasis on health disparities. <br /> National Library of Medicine (NLM) - Est. 1956<br />NLM collects, organizes, and makes available biomedical science information to scientists, health professionals, and the public. The Library's Web-based databases, including PubMed/Medline and MedlinePlus, are used extensively around the world. NLM conducts and supports research in biomedical communications; creates information resources for molecular biology, biotechnology, toxicology, and environmental health; and provides grant and contract support for training, medical library resources, and biomedical informatics and communications research. <br /> Center for Scientific Review (CSR) - Est. 1946<br />CSR is the focal point at NIH for the conduct of initial peer review, the foundation of the NIH grant and award process. The Center carries out peer review of the majority of research and research training applications submitted to the NIH. In addition, the Center serves as the central receipt point for all such Public Health Service (PHS) applications and makes referrals to scientific review groups for scientific and technical merit review of applications and to funding components for potential award. To this end, the Center develops and implements innovative, flexible ways to conduct referral and review for all aspects of science. <br /> John E. Fogarty International Center (FIC) - Est. 1968<br />FIC promotes and supports scientific research and training internationally to reduce disparities in global health. <br /> National Center for Complementary and Alternative Medicine (NCCAM) - Est. 1999<br />NCCAM is dedicated to exploring complementary and alternative medical (CAM) practices in the context of rigorous science; training CAM researchers and disseminating authoritative information. <br /> National Center on Minority Health and Health Disparities (NCMHD) - Est. 1993 <br />The mission of NCMHD is to promote minority health and to lead, coordinate, support, and assess the NIH effort to reduce and ultimately eliminate health disparities. In this effort NCMHD will conduct and support basic, clinical, social, and behavioral research, promote research infrastructure and training, foster emerging programs, disseminate information, and reach out to minority and other health disparity communities. <br /> National Center for Research Resources (NCRR) - Est. 1962<br />NCRR advances biomedical research and improves human health through research projects and shared resources that create, develop, and provide a comprehensive range of human, animal, technological, and other resources. NCRR's support is concentrated in four areas: biomedical technology, clinical research, comparative medicine, and research infrastructure. <br /> NIH Clinical Center (CC) - Est. 1953<br />CC is the clinical research facility of the National Institutes of Health. As a national resource, it provides the patient care, services, and environment needed to initiate and support the highest quality conduct of and training in clinical research. </p><p></p>
 楼主| 发表于 2006-3-14 16:13:04 | 显示全部楼层

美国国立卫生院NIH

<p>与医学信息标准化有关的(搁错了)</p><p> National Library of Medicine (NLM) - Est. 1956<br />NLM collects, organizes, and makes available biomedical science information to scientists, health professionals, and the public. The Library's Web-based databases, including PubMed/Medline and MedlinePlus, are used extensively around the world. NLM conducts and supports research in biomedical communications; creates information resources for molecular biology, biotechnology, toxicology, and environmental health; and provides grant and contract support for training, medical library resources, and biomedical informatics and communications research. </p>
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